146453-40-9

Upstream product

• 4163-60-4 β-D-galactose peracetate 
• 100-39-0 benzyl bromide 
• 97205-08-8 methyl 2,3,4,6-tetra-O-benzyl-1-thio-β-D-galactopyranoside 
• 129163-33-3 4-methoxyphenyl 2,3,4-tri-O-benzyl-β-D-galactopyranoside 
• 887700-91-6 1,2,3,4-tetra-O-acetyl-6-O-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-D-galactopyranose 
• 78148-86-4 D-1’,2’,3’,4’-tetracetyl galactopyranose 
• 53081-30-4 tetra-O-benzyl-α-D-galactosyl bromide 
• 129163-34-4 4-methoxyphenyl O-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-(1->6)-2,3,4-tri-O-benzyl-β-D-galactopyranoside 

Downstream Products

• 29704-64-1 1,6-anhydro-2,3,4-tri-O-benzyl-β-D-galactopyranose 

Relevant academic research and scientific papers

Immunostimulatory activities of monoglycosylated α-D-pyranosylceramides

We compared the immunostimulatory effects of chemically synthesized α-galactosylceramides (α-GalCers), α-glucosylceramides (α-GluCers), 6''- monoglycosylated α-GalCer and 6''- or 4''-monoglycosylated α-GluCer and made the following observations: (1) the length of the fatty acid side chain in the ceramide portions greatly affects the immunostimulatory effects of α-GalCers and α-GluCers; (2) the configuration of the 4''-hydroxyl group of the inner pyranose moiety plays an important role in the immunostimulatory effects of monoglycosylated α-D-pyranosylceramides; (3) the free 4''-hydroxyl group of the inner pyranose of monoglycosylated α-D-pyranosylceramides plays a more important role in their immunostimulatory effects than the free 6''-hydroxyl group.

SYNTHETIC STUDY ON GLYCOPHOSPHATIDYL INOSITOL (GPI) ANCHOR OF TRYPANOSOMA BRUCEI: GLYCOHEPTAOSYL CORE

A stereocontrolled approach to the synthesis of glycoheptaosyl core of glycophosphatidyl inositol (GPI) anchor of Trypanosoma brucei is described for the first time.