146463-36-7

Upstream product

• 130657-41-9 2-acetylamino-6,7-dimethoxy-3-(3,4-dimethoxyphenyl)-1,4-naphthoquinone 
• 127219-95-8 2-amino-6,7-dimethoxy-3-(3,4-dimethoxyphenyl)-1,4-naphthoxyquinone 
• 108-24-7 acetic anhydride 
• 146463-35-6 1,4-diacetoxy-3-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-acetylaminonaphthalene 
• 130657-42-0 2-diacetylamino-6,7-dimethoxy-3-(3,4-dimethoxyphenyl)-1,4-naphthoquinone 

Relevant academic research and scientific papers

SYNTHESIS OF BENZOPHENANTHRIDINES FROM 2-AMINO-6,7-DIMETHOXY-3-(3,4-DIMETHOXYPHENYL)-1,4-NAPHTHOQUINONE

Previously unknown benzophenanthridines with methoxyl substituents in rings A and D were synthesized from 2-amino-6,7-dimethoxy-3-(3,4-dimethoxyphenyl)-1,4-naphthoquinone by N-acylation, reductive acylation, and Bischler-Napieralskii cyclization.The products are of interest in relation to their structural affinity to the highly active antileukemia benzophenanthridine alkaloids.The optimum conditions for the production of 7,12-diacetoxy-5-methyl-2,3,9,10-tetramethoxybenzophenanthridine with high yields were determined.Its hydrolysis by water in boiling dimethyl formamide led to the product from deacetylation at position 7.