146498-75-1

Upstream product

• 7787-60-2 bismuth(III) chloride 
• 59344-64-8 tris(2,4,6-trimethylphenyl)bismuth 

Downstream Products

• 165904-01-8 tetrakis(2,4,6-trimethylphenyl)dibismuthoxide 
• 165904-00-7 tetramesityldibismuthane 

Relevant academic research and scientific papers

Synthesis and crystal structure of tetrakis(2,4,6-trimethylphenyl)dibismuthoxide

Bis(2,4,6-trimethylphenyl)chlorobismuth (1), synthesized by comproportionation reaction of tris(2,4,6-trimethylphenyl)bismuth and bismuth chloride, was reduced with sodium in liquid ammonia. By subsequent insertion of oxygen into the Bi-Bi bond of the int

Reversing Lewis acidity from bismuth to antimony

Investigations on the boundaries between the neutral and cationic models of (Mesityl)2EX (E = Sb, Bi and X = Cl?, OTf?) have facilitated reversing the Lewis acidity from bismuth to antimony. We use this concept to demonstrate a higher efficiency of (Mesityl)2SbOTf(Mesityl)2BiOTf in the catalytic reduction of phosphine oxides to phosphines. The experiments supported with computations described herein will find use in designing new Lewis acids relevant to catalysis.

Activity of antifungal organobismuth(III) compounds derived from alkyl aryl Ketones against S. cerevisiae: Comparison with a heterocyclic bismuth scaffold consisting of a diphenyl sulfone

A series of hypervalent organobismuth(III) compounds derived from alkyl aryl ketones [XBi(5-R′C6H3-2-COR)(Ar)] was synthesized to investigate the effect of the compounds' structural features on their antifungal activity against the yeast Saccharomyces cerevisiae. In contrast to bismuth heterocycles [XBi(5-RC6H3-2-SO 2C6H4-1′-)] derived from diphenyl sulfones, a systematic quantitative structure-activity relationship study was possible. The activity depended on the Ar group and increased for heavier X atoms, whereas lengthening the alkyl chain (R) or introducing a substituent (R′) reduced the activity. IBi(C6H4-2-COCH 3)(4-FC6H4) was the most active. Its activity was superior to that of the related acyclic analogues ClBi[C6H 4-2-CH2N(CH3)2](Ar) and ClBi(C 6H4-2-SO2 tert-Bu)(Ar) and also comparable to that of heterocyclic ClBi(C6H4-2-SO2C 6H4-1′-), which was the most active compound in our previous studies. Density function theory calculations suggested that hypervalent bismuthanes undergo nucleophilic addition with a biomolecule at the bismuth atom to give an intermediate ate complex. For higher antifungal activity, adjusting the lipophilicity-hydrophilicity balance, modeling the three-dimensional molecular structure around the bismuth atom, and stabilizing the ate complex appear to be more important than tuning the Lewis acidity at the bismuth atom.

Element-element bonds. VIII. Synthesis, molecular and crystal structure of dibromo(2,4,6-trimethylphenyl)bismuthane

Dichloro-(1) und dibromo(2,4,6-trimethylphenyl)bismuthane (2) are obtained in relatively high yields from metathesis reactions of the corresponding bismuth(III) halides with tris(2,4,6-trimethylphenyl)bismuthane. An X-ray structure determination of the dibromo derivative 2 (monoclinic, P21/c; a = 896.2(2); b = 1531.9(3); c = 1713.3(3) pm; β = 94.31(3)° at -100 ± 3 °C; Z = 8 molecules; R = 0.059) shows two crystallographically independent molecules to build up a zigzag chain via strong Bi-Br··Bi bridges (Bi-Br 282 and 281; Br··Bi 302 and 302 pm) and relatively weak n6-arene··Bi interactions (mean values Bi··C 348 and 359 pm); for sterical reasons one bromo substituent of each molecule is not involved in coordinative bonding (Bi-Br 262 and 261 pm). To allow a better comparison of Bi-Cipso bond lengths and arene··Bi contacts, relevant values of a greater number of related compounds have been compiled; for some of these examples arene··Bi interactions had not been reported before. Ir and Raman bands below 350 cm-1 are assigned to stretching frequencies of the BiCl2 (1) and BiBr2 (2) fragments, respectively. Keywords: Dichloro(2,4,6-trimethylphenyl)bismuthane: dibromo(2,4,6-trimethylphenyl)bismuthane; crystal structure; Bi-Br··Bi bridges: n6-arene··Bi contacts; ir and Raman data.