1465003-34-2Relevant academic research and scientific papers
Water excellent solvent for the synthesis of bifunctionalized cyclopentenones from furfural
Nardi, Monica,Costanzo,De Nino,Di Gioia,Olivito,Sindona,Procopio
, p. 5403 - 5411 (2017)
Chiral cyclopentenones are important precursors in the asymmetric synthesis of target molecules. In particular, C-2 amino cyclopentenones could be utilised as intermediates towards antitumor natural products. On the basis of our previous experience, we re
Synthesis of 2,4-bifunctionalised cyclopentenones from 2-furaldehyde
Nunes, Joao P.M.,Afonso, Carlos A.M.,Caddick, Stephen
, p. 14975 - 14978 (2013/09/02)
Herein we report a new approach to the synthesis of 2,4-bifunctionalised cyclopentenones via one-pot conversion of 2-furaldehyde with morpholine followed by concomitant 1,4 addition and elimination. This protocol has also been extended to afford 2-hydroxy
