146509-76-4

Upstream product

• 121-69-7 N,N-dimethyl-aniline 
• 83026-11-3 (4-dimethylamino-phenyl)-hydroxy-malonic acid diethyl ester 
• 119-58-4 4,4'-bis(dimethylamino)benzhydrol 
• 924-44-7 glyoxylic acid ethyl ester 
• 681464-91-5 bis-(4-dimethylamino-phenyl)-malonic acid dimethyl ester 
• 74266-38-9 bis-(4-dimethylamino-phenyl)-acetonitrile 

Downstream Products

• 119-58-4 4,4'-bis(dimethylamino)benzhydrol 

Relevant academic research and scientific papers

Friedel-Crafts reaction catalyzed by perfluorinated rare earth metals

The Friedel-Crafts reaction of anisole with acetic anhydride can be carried out in the presence of perfluorinated rare earth metal catalyst without organic solvent. Perfluorodecalin (C10F18, cis- and trans-mixture) can be used as a fluorous phase solvent for this reaction. Whereas, the reaction of N,N-dimethylaniline with acetic anhydride did not give the corresponding Friedel-Crafts reaction product. On the other hand, the Friedel-Crafts reaction of N,N-dimethylaniline with ethyl glyoxylate was also examined in the presence of perfluorinated Lewis acids. Three products were in fact formed at the same time.

Process for preparation 2,6-dihydrobenzo[1:26, 4:5-6]-difuran dyes

A process for the preparation of a polycyclic dye of the Formula (1): STR1 by reacting a substituted acetic acid of the Formula (2): STR2 with a compound of the Formula (3): STR3 and oxidation of the intermediate leuco compound to dehydrogenate the peripheral heterocyclic rings wherein Y is an optionally substituted aromatic or heteroaromatic radical; Ring A is unsubstituted or is substituted by from one to five groups; Z is --NR1 R2 ; R1 and R2 are each independently H or are independently selected from optionally substituted alkyl, alkenyl, cycloalkyl, aralkyl, aryl and heteroaryl; or R1 and R2 together with the nitrogen atom to which they are attached form a heterocyclic ring; or R1 and R2 each independently together with the nitrogen to which they are attached and the adjacent carbon atom of Ring B form a heterocyclic ring; and X1 and X2 are each independently selected from H, halogen, optionally substituted alkyl, optionally substituted aryl, optionally substituted heteroaryl, cyano, carbamoyl, sulphamoyl, carboxylic acid and carboxylic acid ester, a process for the preparation of the substituted acetic acid of Formula (2) and certain novel substituted acetic acids of Formula (2).