146533-54-2Relevant articles and documents
ARTIFICIAL METALLOENZYMES CONTAINING NOBLE METAL-PORPHYRINS
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Paragraph 0290; 0293; 0294, (2018/11/21)
The present invention is drawn to artificial metalloenzymes for use in cyclopropanation reactions, amination and C—H insertion.
Chemoselective, enzymatic C-H bond amination catalyzed by a cytochrome P450 containing an Ir(Me)-PIX cofactor
Dydio, Pawel,Key, Hanna M.,Hayashi, Hiroki,Clark, Douglas S.,Hartwig, John F.
, p. 1750 - 1753 (2017/02/15)
Cytochrome P450 enzymes have been engineered to catalyze abiological C-H bond amination reactions, but the yields of these reactions have been limited by low chemoselectivity for the amination of C-H bonds over competing reduction of the azide substrate t