146579-86-4Relevant academic research and scientific papers
Diastereoselective addition of silyl enol ether to chiral imines and 1,3-oxazolidines using a Lewis acid
Higashiyama, Kimio,Kyo, Hideyoshi,Takahashi, Hiroshi
, p. 489 - 490 (2007/10/03)
The Lewis acid promoted reaction of silyl enol ether to chiral imines and 1,3-oxazolidines derived from (R)-phenylglycinol afforded with good diastereoselectivity the (R,R)-β-amino ester derivatives from the imines, and the (R,S)-β-amino ester derivatives from the 1,3-oxazolidines.
An Efficient Enantiomeric Three Step Synthesis of β-Amino Acids (Esters)
Mokhallalati, Mohamed K.,Wu, Ming-Jung,Pridgen, Lendon N.
, p. 47 - 50 (2007/10/02)
Ethyl tributylstannylacetate was reacted with (R)-2-aryl or alkyl-1,3-oxazolidines 6 under very specific (ZnCl2/Et2O*BF3, 0.5 equiv each) Lewis Acid catalyzed conditions to yield (1R,1'R)-N-2'-hydroxy-1'-phenylethyl-1-aryl or alkyl-2-carboethoxyethylamine
