146582-86-7

Upstream product

• 74-88-4 methyl iodide 
• 77697-15-5 (R)-(-)-γ-benzyloxymethyl-γ-butyrolactone 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 
• 52813-63-5 (5R)-2,3,4,5-tetrahydro-5-hydroxymethyl-2-furanone 
• 865-34-9 lithium methanolate 

Downstream Products

• 93292-90-1 (R)-4-Acetoxy-5-benzyloxy-pentanoic acid methyl ester 
• 381718-98-5 Methyl (R)-5-O-benzyl-4-O-tert-butyldimethylsilyl-4,5-dihydroxypentanoate 
• 98892-19-4 5-benzyloxy 4R-t-butyldimethylsiloxy 1-pentanol 
• 381718-99-6 (R)-5-O-Benzyl-4-O-tert-butyldimethylsilyl-4,5-dihydroxypentanal 
• 381719-04-6 (R)-1-O-Benzyl-5-ethylenedithio-1,2-decandiol 
• 381719-00-2 (2R),(5RS)-1-O-Benzyl-2-O-tert-butyldimethylsilyl-1,2,5-decantriol 
• 381719-01-3 1-benzyloxy-2-(tert-butyl-dimethyl-silanyloxy)-decan-5-one 
• 381719-06-8 (R)-1-O-Benzyl-2-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-5-ethylenedithio-1,2-decandiol 
• 381719-05-7 (R)-1-O-Benzyl-2-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-5-ethylenedithio-1,2-decandiol 
• 85700-43-2 5E,7E-Clavulone II 

Relevant academic research and scientific papers

Novel chiral glycerol analogues building blocks. Application to the synthesis of bioactive glycoglycerolipid analogues

Monoacylglycosylglycerols show anti-tumor promoting effects: in order to study the role of the ester function we have prepared by simple methods (R)-1-O-benzyl-1,2-decandiol, (R)-3-O-benzyl-1-O-hexyl-sn-glycerol, and (R)-1-O-benzyl-5-oxo-1,2-decandiol; these optically active compounds are building blocks for the synthesis of monohexanoylglycosylglycerol isosters.

TOTAL SYNTHESIS OF MARINE PROSTANOIDS CLAVULONES

An enantioselective and stereoselective synthesis of novel marine prostanoids clavulone II (1) and 12-O-desacetylclavulone II (2) has been accomplished.