865-34-9 Usage
Preparation
Lithium methoxide (3 cm3, 3mmol of 1.0M solution in methanol) was added to ?(11) (1.0 g, 2.8 mmol) in methanol (15 cm3) at 0 °C, with stirring, under an atmosphere ?of nitrogen. The mixture was stirred at room temperature for 67 h, then water (20 cm3) ?was added and the mixture extracted into dichloromethane (DCM). The DCM solution ?was dried (MgS04) and evaporated giving a solid ( 1.1 g) shown to consist of 4- methoxy-3,5-difluoro-2,6-dibromopyridine (22g) ( 19% ), 2,6-dibromo-4,5-dimethoxy-3- fluoropyridine (22h) (5%), (23b) (39% by comparison with authentic sample) and (23a) ?(36%). Neither column chromatography (eluting DCM and petrol 7: 3) nor preparative ?scale GLC ( 10% SE30, 140 oC) gave adequate separation of the products. However, a ?carbon nmr spectrum and GCMS of a mixture of (22g) and (23b) was obtained and the ?carbon spectra was assigned by comparison with that of (23b ).
Chemical Properties
white powder
Uses
Different sources of media describe the Uses of 865-34-9 differently. You can refer to the following data:
1. Lithium methoxide is used in sol-gel synthesis of lithium borophosphates. It is also useful for deprotonation reactions in organic synthesis. Further, it serves as a mild base in organic synthesis especially in transesterifications.
2. Employed in sol-gel synthesis of lithium borophosphates.
Purification Methods
The most probable impurity is LiOH due to hydrolysis by moisture. It is important to keep the sample dry. It can be dried by keeping in a vacuum at 60-80o under dry N2 using an oil pump for a few hours. Store it under N2 in the cold. It should not have bands above 3000cm-1, IR has 1078, 2790, 2840 and 2930cm-1 in KBr. [Suebold J Org Chem 21 1561956, Beilstein 1 IV 1220, 1241.]
Check Digit Verification of cas no
The CAS Registry Mumber 865-34-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,6 and 5 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 865-34:
(5*8)+(4*6)+(3*5)+(2*3)+(1*4)=89
89 % 10 = 9
So 865-34-9 is a valid CAS Registry Number.
InChI:InChI=1/CH3O.Li/c1-2;/h1H3;/q-1;+1/rCH3LiO/c1-3-2/h1H3
865-34-9Relevant articles and documents
Synthesis and structure of hypercoordinated germanate complexes with naphthalene-2,3-dialkoxide ligands
Goto, Mitsuki,Nakashima, Yuta,Nanjo, Masato
, (2021/09/15)
The synthesis of six-coordinated germanate complexes with naphthalene-2,3-dialkoxide ligands with alkali metals (Li, Na, and K) as counter ions are described. The molecular structures of lithium and potassium germanate complexes were clarified by X-ray diffraction analysis. Each germanium center atom is coordinated by six oxygen atoms to form slightly distorted octahedral configuration. All the compounds were thermally stable up to 300 °C determined by thermogravimetric analysis under air-flow conditions.
Complexes of the gilman reagent with double bonds across the π-σ Continuum
Bertz, Steven H.,Cope, Stephen K.,Hardin, Richard A.,Murphy, Michael D.,Ogle, Craig A.,Smith, David T.,Thomas, Andy A.,Whaley, Tara N.
, p. 7827 - 7838 (2013/01/16)
By using rapid injection NMR at low temperatures, a variety of π-complexes of lithium dimethylcuprate(I) with C-C, C-N, and C-S double bonds have been prepared and characterized. Complexation is generally accompanied by large upfield changes in chemical shift for the substrate carbon atoms bonded to copper. In the case of α,β-unsaturated carbonyl compounds, the changes for the carbonyl carbons are much smaller in magnitude, which is consistent with the usual η2 representation of these structures. It is possible for one ligand to displace another, and in this way an order of stability can be elucidated. Treatment of selected π-complexes with chlorosilanes or cyanosilanes gives CuIII intermediates.
X-ray crystal structure and hydrocarbon solution behaviour of tetrameric 2,2-Bis(methoxymethyl)-1-propyllithium
Moene,Schakel,Hoogland,De Kanter,Klumpp,Spek
, p. 2641 - 2642 (2007/10/02)
The title compound is a tetramer in the solid state and in hydrocarbon solution.
