146604-41-3 Usage
Uses
Used in Pharmaceutical Research:
Thymidine, 3'-deoxy-3'-(hydroxymethyl)-5'-O-(triphenylmethyl)is utilized as a nucleotide analog in the development of antiviral and anticancer drugs. Its unique structure enhances the stability and specificity of these drugs, potentially leading to more effective treatments.
Used in Biochemical Research:
This modified thymidine serves as a research tool for studying the structure and function of nucleic acids. It aids in understanding the interactions between nucleic acids and proteins or other molecules, contributing to the advancement of molecular biology.
Used in Drug Development:
In the pharmaceutical industry, Thymidine, 3'-deoxy-3'-(hydroxymethyl)-5'-O-(triphenylmethyl)is employed as a precursor in the synthesis of novel therapeutic agents. Its unique properties allow for the creation of drugs with improved pharmacokinetics and pharmacodynamics, enhancing their efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 146604-41-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,6,0 and 4 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 146604-41:
(8*1)+(7*4)+(6*6)+(5*6)+(4*0)+(3*4)+(2*4)+(1*1)=123
123 % 10 = 3
So 146604-41-3 is a valid CAS Registry Number.
146604-41-3Relevant academic research and scientific papers
Synthesis of 5'-phosphonate linked thymidine deoxyoligonucleotides
Kofoed, Thomas,Caruthers, Marvin H.
, p. 6457 - 6460 (2007/10/03)
5'-Deoxy-5'-phosphonothymidine was synthesized and coupled with 3'-deoxy-3'-hydroxy-methylthymidine to yield a 3'-C-O-P-5' linked thymidine dinucleotide. This dimer as its 3'-phosphoramidite was used to synthesize deoxyoligonucleotides.
