146606-69-1

Basic information

• Product Name: 3-(4-chlorophenyl)-2-methylpyrimido[4',5':4,5]thieno[2,3-b]quinolin-4(3H)-one
• Synonyms: 3-(4-chlorophenyl)-2-methylpyrimido[4',5':4,5]thieno[2,3-b]quinolin-4(3H)-one
• CAS NO: 146606-69-1
• Molecular Formula: C20H12ClN3OS
• Molecular Weight: 377.84678
• Mol File: 146606-69-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(4-chlorophenyl)-2-methylpyrimido[4',5':4,5]thieno[2,3-b]quinolin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-chlorophenyl)-2-methylpyrimido[4',5':4,5]thieno[2,3-b]quinolin-4(3H)-one(146606-69-1)
• EPA Substance Registry System: 3-(4-chlorophenyl)-2-methylpyrimido[4',5':4,5]thieno[2,3-b]quinolin-4(3H)-one(146606-69-1)

Safety Data

• Hazardous Substances Data: 146606-69-1(Hazardous Substances Data)

Upstream product

• 146606-49-7 2-(3-Cyano-quinolin-2-ylsulfanyl)-N-(4-methoxy-phenyl)-acetamide 
• 146606-50-0 N-(4-Chloro-phenyl)-2-(3-cyano-quinolin-2-ylsulfanyl)-acetamide 
• 146606-52-2 3-Amino-thieno[2,3-b]quinoline-2-carboxylic acid (4-methoxy-phenyl)-amide 
• 146606-53-3 3-Amino-thieno[2,3-b]quinoline-2-carboxylic acid (4-chloro-phenyl)-amide 
• 146606-51-1 3-Amino-thieno[2,3-b]quinoline-2-carboxylic acid phenylamide 
• 146606-48-6 2-((3-cyanoquinolin-2-yl)thio)-N-phenylacetamide 
• 69513-35-5 3-Cyanoquinoline-2(1H)-thione 
• 95104-21-5 2-chloroquinoline-3-carbonitrile 
• 106-47-8 4-chloro-aniline 
• 146606-66-8 2-methyl-4-oxo-oxazino<4',5':4,5>thieno<2,3-b>quinoline 

Relevant articles and documents

SYNTHESIS AND REACTIONS OF SOME NEW 3-AMINO-2-SUBSTITUTED THIENOQUINOLINES

Reaction of 3-cyano-quinolin-2(1H)-thione (II) with ω-bromoacetophenones gave 3-amino-2-aroyl-thienoquinolines (IVa - IVd).Whereas, interaction of II with chloroacetanilides yielded the corresponding thioethers Va - Vc which cyclized into 3-amino-2-arylcarbamoylthienequinolines (VIa - VIc) on treatment with ethoxide.Compounds VIa - VIc were reacted with nitrous acid, triethyl orthoformate and carbon disulfide to afford the fused polycyclic compounds VIIa - VIIc, VIIIa - VIIIc, and IXa - IXc, respectively.Also, treatment of IXa - IXc with ethyl iodide gave 3-ethylthio derivatives Xa- Xc.Moreover, refluxing of VIa - VIc with acetic anhydride resulted in the formation of oxazinone XI which recyclized into pyrimidinones XIIIa - XIIIc upon reaction with aromatic amines.