146669-29-6 Usage
Uses
(RS)-MCPG is a non-selective group I/group II metabotropic glutamate receptor antagonist.
Biological Activity
Non-selective group I/group II metabotropic glutamate receptor antagonist. See (S)-isomer ((S)-a-Methyl-4-carboxyphenylglycine ).
Check Digit Verification of cas no
The CAS Registry Mumber 146669-29-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,6,6 and 9 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 146669-29:
(8*1)+(7*4)+(6*6)+(5*6)+(4*6)+(3*9)+(2*2)+(1*9)=166
166 % 10 = 6
So 146669-29-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H11NO4/c1-10(11,9(14)15)7-4-2-6(3-5-7)8(12)13/h2-5H,11H2,1H3,(H,12,13)(H,14,15)/p-1/t10-/m1/s1
146669-29-6Relevant articles and documents
Resolution and regioselective protection of glutamic acid analogues. II - Synthesis, resolution and configuration assignment of (+)-α-methyl-4-carboxyphenylglycine (M4CPG)
Coudert, Elisabeth,Acher, Francine,Azerad, Robert
, p. 2963 - 2970 (2007/10/03)
Diastereomeric dipeptides (S)-Leu-(S)-M4CPG and (S)-Leu-(R)-M4CPG have been synthesized from (±)-M4CPG and separated by anion exchange chromatography. Absolute configuration of (S)-(+)-M4CPG was assigned by X-Ray crystallography of (S)-Leu-(S)-M4CPG.
