14667-95-9Relevant academic research and scientific papers
Novel coupling reaction between sulfonyl azide and N,N,N',N'-tetramethylthiourea
Aswad, Muhammad,Chiba, Junya,Hatanaka, Yasumaru,Tomohiro, Takenori
, p. 1611 - 1613 (2019)
The synthesis of sulfonylguanidines from N,N,N',N'-tetramethylthiourea and sulfonyl azides is described. This method serves as an alternative route for generating sulfonylguanidines via the use of stable starting materials.
Facile one-pot synthesis of tetrasubstituted N-sulfonylguanidines from sulfonamides and ureas
Wang, Fei,Yumaier, Abulimiti,Wusiman, Abudureheman
, p. 993 - 999 (2021/08/12)
A facile method for the synthesis of tetrasubstituted N-sulfonylguanidines has been developed via the direct condensation of sulfonamides and ureas in the presence of phosphoryl chloride under basic conditions. Detailed synthetic studies showed that this is a simple protocol for preparing N-sulfonylguanidines at room temperature in a short reaction time with good to excellent yields. Graphic abstract: [Figure not available: see fulltext.].
N -Sulfonyl acetylketenimine as a highly reactive intermediate for the synthesis of N -sulfonyl amidines
Yang, Weiguang,Huang, Dayun,Zeng, Xiaobao,Luo, Dongping,Wang, Xinyan,Hu, Yuefei
supporting information, p. 8222 - 8225 (2018/07/29)
A highly reactive intermediate N-sulfonyl acetylketenimine was generated from a 3-butyn-2-one participating CuAAC/ring-opening method. Its high reactivity due to bearing two EWGs allowed us to offer the first example of a reaction between ketenimine and amide to synthesize N-sulfonyl amidines efficiently.
