14674-18-1Relevant articles and documents
Access to 1,4-Dihydrobenzo[e][1,2,4]triazin-4-yl Derivatives
Constantinides, Christos P.,Obijalska, Emilia,Kaszyński, Piotr
supporting information, p. 916 - 919 (2016/03/15)
A simple, one-pot method for the preparation of 1-aryl-3-phenyl-1,4-dihydrobenzo[e][1,2,4]triazin-4-yl radicals by addition of aryllithium to the readily available 3-phenylbenzo[e][1,2,4]triazine followed by aerial oxidation is described. The intermediate
Pyrido[3,4-e]-1,2,4-triazines and related heterocycles as potential antifungal agents
Reich,Fabio,Lee,Kuck,Testa
, p. 2474 - 2485 (2007/10/02)
The preparation and biological activities of a series of pyrido[3,4-e]-1,2,4-triazines, 1,2,4-triazino[5,6-c]quinolines, and related fused triazines are described. Methyl, amino, and acylamino substituents were placed in the pyridyl ring of the former system. Other structural modifications included various alkyl, cycloalkyl, substituted phenyl, and heterocyclic groups in the 3-position of these ring systems. In agar dilution assays, actives in this series inhibited strains of Candida, Aspergillus, Mucor, and Trychophyton species at MIC's of ≤ 16 μg/mL.