14674-35-2

Upstream product

• 70-55-3 toluene-4-sulfonamide 
• 552-89-6 2-nitro-benzaldehyde 
• 4104-47-6 N-sulfinyl-p-toluenesulfonamide 

Downstream Products

• 1112116-60-5 (S)-N-[(2-nitrophenyl)phenylmethyl]-4-methylbenzenesulfonamide 
• 1228802-92-3 N-((2,6-dimethoxyphenyl)(2-nitrophenyl)methyl)-4-methylbenzenesulfonamide 
• 1236009-80-5 C₁₅H₁₄N₂O₄S 
• 1296868-36-4 2-methyl-1-[(4-methylphenyl)sulfonyl]-5-(2-nitrophenyl)-1H-pyrrole 
• 104384-61-4 2-methyl-5-(2-nitrophenyl)-1H-pyrrole 
• 1264626-31-4 C₃₀H₃₄N₂O₅SSi 

Relevant academic research and scientific papers

Access to 3-Sulfonamidoquinolines by Gold-Catalyzed Cyclization of 1-(2′-Azidoaryl)propargylsulfonamides through 1,2- N Migration

We describe a gold-catalyzed cyclization of 1-(2′-azidoaryl)propargylsulfonamides for the synthesis of 3-sulfonamidoquinolines, featuring a rare and highly selective 1,2-N migration. The key α-imino gold carbene intermediate is generated through an intram

One-Pot Synthesis of Diazirines and 15N2-Diazirines from Ketones, Aldehydes and Derivatives: Development and Mechanistic Insight

Broad scope one-pot diazirine synthesis strategies have been developed using two different oxidants depending on the nature of the starting material. In all cases, an inexpensive commercial solution of ammonia (NH3) in methanol (MeOH) was emplo

Facile synthesis, antimicrobial and antiviral evaluation of novel substituted phenyl 1,3-thiazolidin-4-one sulfonyl derivatives

A series of novel substituted phenyl 1, 3-thiazolidin-4-one sulfonyl derivatives 5 (a-t) were synthesized and screened for their in-vitro anti-microbial and anti-viral activity. The result of the anti-microbial assay demonstrated compounds 5d, 5f, 5g, 5h,

Mild Darzens Annulations for the Assembly of Trifluoromethylthiolated (SCF3) Aziridine and Cyclopropane Structures

We report mild new annulation approaches to trisubstituted trifluoromethylthiolated (SCF3) aziridines and cyclopropanes via Darzens inspired protocols. The products of these anionic annulations, rarely studied previously, possess attractive features rendering them valuable building blocks for synthesis platforms. In this study, trisubstituted acetophenone nucleophiles bearing SCF3 and bromine substituents in their α position were shown to undergo [2 + 1] annulations with vinyl ketones and tosyl-protected imines under mild reaction conditions.

Strategic vinyl sulfone nucleophile β-substitution significantly impacts selectivity in Vinylogous Darzens and aza-Darzens reactions

Vinylogous Darzens and aza-Darzens reactions employing a benzothiophene 1,1-dioxide nucleophile are reported. These new [2 + 1] annulation reactions, which proceed under mild reaction conditions, are γ-selective, affording trans-epoxides selectively and favoring trans-aziridines. The reactions are base-dependent, with KOtBu and Cs2CO3 being optimal for aldehyde and imine annulations, respectively. Comparison of the benzothiophene nucleophile to its acyclic counterpart reveals superior performance in the case of aldehydes, while the outcome varies depending on the sulfonamide imine used.

One-pot nitro-Mannich/hydroamination cascades for the direct synthesis of 2,5-disubstituted pyrroles using base and gold catalysis

An efficient, easy to perform, one-pot reaction cascade for the synthesis of 2,5-disubstituted pyrroles from p-toluenesulfonyl protected imines and 4-nitrobut-1-yne under a combination of base and gold(iii) catalysis is reported.

A novel method for the synthesis of N-sulfonylaldimines by ZnO as a recyclable neutral catalyst under solvent-free conditions

ZnO acts as an effective catalyst for the rapid synthesis of a range of N-sulfonylaldimines from aromatic aldehydes and sulfonamides under solvent free conditions. The ZnO powder can be reused up to three times after simple washing with distilled water and ethyl acetate.

2-(4-Toluenesulphonyl)-3-aryloxaziridines as Oxidizing Reagents for P(III) Compounds

The preparation of four 2-(4-toluenesulphonyl)-3-aryloxaziridines by oxidation of the corresponding imines by peracids is described.The relative oxidation rates of trimethyl phosphite by these oxaziridines are determined. Key words: 2-(4-Toluenesulphonyl)