146763-62-4

Basic information

• Product Name: (31R)-4,8:7,11:10,14:13,17:16,21:20,24:23,27:26,31-octaanhydro-2,3,5,9,12,15,18,19,22,25,28,29-dodecadeoxy-31-[(1Z,3Z)-hepta-1,3,6-trien-1-yl]-7,11,21,23-tetramethyl-30-C-methyl-D-glycero-D-allo-D-allo-D-allo-D-allo-hentriacont-28-enitol
• Synonyms: gambierol
• CAS NO: 146763-62-4
• Molecular Formula: C₄₃H₆₄O₁₁
• Molecular Weight: 756.9617
• Mol File: 146763-62-4.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 823.7°C at 760 mmHg
• Flash Point: 452°C
• Density: 1.18g/cm³
• Vapor Pressure: 1.87E-31mmHg at 25°C
• Refractive Index: 1.548
• CAS DataBase Reference: (31R)-4,8:7,11:10,14:13,17:16,21:20,24:23,27:26,31-octaanhydro-2,3,5,9,12,15,18,19,22,25,28,29-dodecadeoxy-31-[(1Z,3Z)-hepta-1,3,6-trien-1-yl]-7,11,21,23-tetramethyl-30-C-methyl-D-glycero-D-allo-D-allo-D-allo-D-allo-hentriacont-28-enitol(CAS DataBase Reference)
• NIST Chemistry Reference: (31R)-4,8:7,11:10,14:13,17:16,21:20,24:23,27:26,31-octaanhydro-2,3,5,9,12,15,18,19,22,25,28,29-dodecadeoxy-31-[(1Z,3Z)-hepta-1,3,6-trien-1-yl]-7,11,21,23-tetramethyl-30-C-methyl-D-glycero-D-allo-D-allo-D-allo-D-allo-hentriacont-28-enitol(146763-62-4)
• EPA Substance Registry System: (31R)-4,8:7,11:10,14:13,17:16,21:20,24:23,27:26,31-octaanhydro-2,3,5,9,12,15,18,19,22,25,28,29-dodecadeoxy-31-[(1Z,3Z)-hepta-1,3,6-trien-1-yl]-7,11,21,23-tetramethyl-30-C-methyl-D-glycero-D-allo-D-allo-D-allo-D-allo-hentriacont-28-enitol(146763-62-4)

Safety Data

• Hazardous Substances Data: 146763-62-4(Hazardous Substances Data)

Usage

General Description

The chemical "(31R)-4,8:7,11:10,14:13,17:16,21:20,24:23,27:26,31-octaanhydro-2,3,5,9,12,15,18,19,22,25,28,29-dodecadeoxy-31-[(1Z,3Z)-hepta-1,3,6-trien-1-yl]-7,11,21,23-tetramethyl-30-C-methyl-D-glycero-D-allo-D-allo-D-allo-D-allo-hentriacont-28-enitol" is a complex and long-chain molecule. It contains multiple methyl groups and a hepta-1,3,6-trien-1-yl side chain. The molecule also has multiple hydroxyl groups and is comprised of dodecadeoxy units. Additionally, it contains a C-methyl-D-glycero-D-allo-D-allo-D-allo-D-allo-hentriacont-28-enitol structure. It is a highly specialized and intricate compound with a specific configuration and arrangement of atoms.

Upstream product

• 213815-44-2 (Z)-1-tributylstannyl-1,4-pentadiene 
• 213815-44-2 C₁₇H₃₄Sn 
• 457058-86-5 C₆₆H₁₀₃BrO₁₁Si₃ 
• 457058-88-7 C₃₈H₅₇BrO₁₁ 
• 494760-51-9 C₅₃H₉₁IO₁₁Si₂ 

Relevant articles and documents

Total synthesis of gambierol by using oxiranyl anions

Gambierol was isolated as a neurotoxin from the cultured cells of the ciguatera causative dinoflagellate Gambierdiscus toxicus and classified as a member of the polycyclic ether family of marine toxins. The structure consists of a ladder-shaped frans-fuse

Total synthesis of gambierol

The total synthesis of gambierol has been achieved utilizing an oxiranyl anion strategy in an iterative manner. Synthetic highlights of this route include direct carbon-carbon formation on epoxides, sulfonyl-assisted 6-endo cyclization, and expansion reac

Diverted total synthesis and biological evaluation of gambierol analogues: Elucidation of crucial structural elements for potent toxicity

Gambierol is a polycyclic ether toxin, which has been isolated from the marine dinoflagellate Gambierdiscus toxicus. A series of gambierol analogues have been prepared from an advanced intermediate of our total synthesis of gambierol and investigated for