213815-44-2Relevant academic research and scientific papers
Lewis acid catalyzed allylstannylation of unactivated alkynes
Matsukawa, Yasuhisa,Asao, Naoki,Kitahara, Haruo,Yamamoto, Yoshinori
, p. 3779 - 3790 (1999)
The addition of allyltributylstannane 2 to unactivated aromatic alkynes 1 in the presence of catalytic amounts of ZrCl4 or EtAlCl2 produced the stannylated 1,4-dienes 3 with very high regio- and stereoselectivities in good to high yi
Total Synthesis of the Potent HIF-1 Inhibitory Antitumor Natural Product, (8R)-Mycothiazole, via Baldwin-Lee CsF/CuI sp3-sp2-Stille Cross-Coupling. Confirmation of the Crews Reassignment
Wang, Liping,Hale, Karl J.
, p. 4200 - 4203 (2015/09/15)
A convenient asymmetric total synthesis of the potent HIF-1 inhibitory antitumor natural product, (-)- or (+)-(8R)-mycothiazole (1), is described. Not only does our synthesis confirm the 2006 structural reassignment made by Crews (Crews, P., et al. J. Nat
Lewis acid-catalyzed hydrometalation and carbometalation of unactivated alkynes
Asao, Naoki,Yamamoto, Yoshinori
, p. 1071 - 1087 (2007/10/03)
Hydrosilylation, hydrostannation, carbosilylation, and carbostannation of unactivated alkynes with organosilanes, or organostannanes proceed effectively in the presence of catalytic amounts of Lewis acids to produce the corresponding vinylsilyl or vinylst
