14677-96-4

Upstream product

• 1013-88-3 Benzophenone imine 
• 698-16-8 benzohydroximoyl chloride 
• 932-90-1 Benzaldoxime 
• 1451067-54-1 (Z)-N,N-dibenzyl-N'-hydroxybenzimidamide 
• 121-44-8 triethylamine 
• 873-67-6 benzonitrile oxide 

Downstream Products

• 31730-65-1 2,4-diphenylquinazoline 

Relevant academic research and scientific papers

3,5,5-Triphenyl-4,5-dihydro-1,2,4-oxadiazole

Reaction of benzophenone imine with benzeneoximoyl chloride performed in the presence of triethylamine in diethyl ether affords the title compound, C20H16N2O. In the crystalline state, the product exists in two conformations differing in the orientation of the 3-phenyl substituent with respect to the heterocyclic ring. N -H...N hydrogen bonds link the molecules into chains parallel to the b axis.

Transformation of 5,5-diaryl-4,5-dihydro-1,2,4-oxadiazoles to 4-arylquinazolines

The transformation of 5,5-diaryl-4,5-dihydro-1,2,4-oxadiazoles to 4-arylquinazolines in boiling acetic anhydride via acyclic 1-acetyloxy-4-aryl-1,3-diaza-1,3-butadienes is described.

Orthogonal aerobic conversion of N-benzyl amidoximes to 1,2,4-oxadiazoles or quinazolinones

Concise synthesis of 1,2,4-oxadiazoles was achieved by heating N-benzyl amidoximes with K3PO4 in DMF at 60°C under an O 2 atmosphere via benzylic C-H oxygenation. On the other hand, aerobic treatment of N-benzyl amidoximes