146777-98-2Relevant academic research and scientific papers
New anti-inflammatory/anti-arthritic heterocyclic bisphosphonates
Nugent, Richard A.,Dunn, Colin J.,Staite, Nigel D.,Murphy, Michael J.,Schlachter, Stephen T.,Aspar, Danielle G.,Shields, Sharon K.,Galinet, Louise A.
, p. 229 - 232 (2007/10/03)
In the course of research toward a safe and effective treatment for rheumatoid arthritis, we identified new pyrazolo[1,5-a]pyrimidine and 4-pyrimidinone bisphosphonate esters, which are potent inhibitors of a murine model of chronic, cutaneous inflammatio
Pyrazolopyrimidine and pyrimidinyl bisphosphonic esters as anti-inflammatories
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, (2008/06/13)
Compounds useful in the treatment of inflammation structurally represented as STR1 wherein X is O or S and the R groups are as herein defined. The compounds are useful as anti-inflammatory and anti-arthritic agents without inhibiting prostaglandin synthes
