87119-67-3Relevant articles and documents
A one-pot process for the microwave-assisted synthesis of 7-substituted pyrazolo[1,5-a]pyrimidine
Bassoude, Ibtissam,Tber, Zahira,Essassi, El Mokhtar,Guillaumet, Gérald,Berteina-Raboin, Sabine
, p. 3301 - 3306 (2016/01/15)
An efficient synthesis of 7-substituted pyrazolo[1,5-a]pyrimidines using a one-pot, two-step process via Pd-catalyzed direct CH-arylation followed by a saponification-decarboxylation reaction is reported. Compared to the classical method (Negishi coupling), this new procedure has the advantages of convenient manipulation, short reaction times, excellent yields and the use of commercially available and relatively non-toxic compounds.
Catalyst- and base-controlled site-selective sp2 and sp 3 direct arylation of 5,7-dimethyl-2-phenylpyrazolo[1,5-a]pyrimidine using aryl bromides
Bassoude, Ibtissam,Berteina-Raboin, Sabine,Massip, Stephane,Leger, Jean-Michel,Jarry, Christian,Essassi, El Mokhtar,Guillaumet, Gerald
experimental part, p. 2572 - 2578 (2012/06/01)
The palladium-catalyzed direct C-H arylation of various heterocyclic is now recognized to be the most effective methodology for making aromatic compounds. In this paper, we present a new approach to control the site-selective direct C-H arylation of both
Facile synthesis of fluorinated 2-aryl-5,7 bisalkyl pyrazolo pyrimidines from arylalkyne nitriles
Rama Rao,Lingaiah,Ezikiel,Yadla,Shanthan Rao
, p. 275 - 280 (2007/10/03)
Synthesis of pyrazolopyrimidines from fluorine substituted arylalkynenitriles is described. Arylalkynenitriles 1a-d reacted with hydrazine to give 5-aryl-3-amino-2H-pyrazoles 2a-d. The condensation of aminopyrazoles with 1,3-dicarbonyl compounds furnished