14679-00-6

Basic information

• Product Name: 1-(3-Methoxyphenyl)-1H-pyrazol-5-amine
• Synonyms: 1-(3-Methoxyphenyl)-1H-pyrazol-5-amine;2-(3-Methoxyphenyl)-2H-pyrazol-3-ylamine
• CAS NO: 14679-00-6
• Molecular Formula: C₁₀H₁₁N₃O
• Molecular Weight: 189.21384
• Mol File: 14679-00-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(3-Methoxyphenyl)-1H-pyrazol-5-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-Methoxyphenyl)-1H-pyrazol-5-amine(14679-00-6)
• EPA Substance Registry System: 1-(3-Methoxyphenyl)-1H-pyrazol-5-amine(14679-00-6)

Safety Data

• Hazardous Substances Data: 14679-00-6(Hazardous Substances Data)

Usage

Uses

Used in Medicinal Chemistry:
1-(3-Methoxyphenyl)-1H-pyrazol-5-amine is used as a building block for the synthesis of new pharmaceutical compounds due to its potential biological activity and versatility in chemical reactions.
Used in Drug Discovery and Development:
In the field of drug discovery and development, 1-(3-Methoxyphenyl)-1H-pyrazol-5-amine is used for its potential to exhibit properties of interest, which may contribute to the creation of novel therapeutic agents.
Used in Chemical Reactions and Transformations:
1-(3-Methoxyphenyl)-1H-pyrazol-5-amine is utilized in various chemical reactions and transformations, showcasing its potential utility in the synthesis of new compounds for a wide range of applications across different industries.

Upstream product

• 1820-80-0 3-aminopyrazole 
• 766-85-8 3-methoxy-1-iodobenzene 

Relevant articles and documents

Copper(I)/Copper(II)-Assisted Tandem Catalysis: The Case Study of Ullmann/Chan-Evans-Lam N1,N3-Diarylation of 3-Aminopyrazole

Unprecedented CuI/CuII-assisted tandem catalysis allowing an Ullmann/Chan-Evans-Lam sequence was achieved. This three-component, one-pot reaction triggered by a change in the oxidation state of the metal leads to the selective N1,N3-diarylation of 3-aminopyrazole. This new method should be a valuable tool for small-molecule drug discovery that requires suitable regio- and/or chemoselective strategies for the N-arylation of nitrogen-containing heterocycles. Tandem power: The first assisted tandem copper-catalyzed process, triggered by a change in the oxidation state of the metal, is developed to allow a one-pot Ullman/Chan-Evans-Lam sequence leading to the selective N1,N3-diarylation of 3-aminopyrazole.

TETRAZOLE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS

The invention relates to tetrazole compounds of formula (I) wherein X, Y, Z, R1, R2 and R3 are as described in the description; to pharmaceutically acceptable salts thereof, and to the use of such compounds use as medicaments, especially as orexin receptor antagonists.

TETRAZOLE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS

The invention relates to tetrazole compounds of formula (I) wherein X, Y, Z, R1, R2 and R3 are as described in the description; to pharmaceutically acceptable salts thereof, and to the use of such compounds use as medicaments, especially as orexin receptor antagonists.