146860-53-9

Upstream product

• 1817-20-5 4-chloro-2,6-bis(hydroxymethyl)pyridine 
• 622-08-2 2-Benzyloxyethanol 
• 146860-52-8 4-(2-benzyloxyethoxy)-pyridine-2,6-dimethanol 

Downstream Products

• 146860-54-0 16-(2-benzyloxyethtoxy)-6,9-dioxa-3,12,18-triazabicyclo<12.3.1>octadeca-1(18),14,16-trien 
• 146860-55-1 26-(2-benzyloxyethoxy)-17,20-dioxa-1,14,30-triazatricyclo<12.8.7.1^24,28>triaconta-24,26,28(30)-trien-2,13-dione 

Relevant academic research and scientific papers

Concave Reagents. 12. Polymerfixation of Concave Pyridines

Via a metal ion template directed synthesis and a high dilution cyclization, a bimacrocyclic 4-benzyloxyethoxy-substituted concave pyridine 8 was synthesized from dialdehyde 3, diamine 4 and diacyl dichloride 7 in 54percent overall yield.Pd-catalyzed hydrogenolysis of 8 afforded the OH-substituted concave pyridine 9 which could be attached to a Merrifield resin 10 after deprotonation with NaH.The modified polymer 11 contained 10percent (w/w) of 8.