146919-83-7Relevant academic research and scientific papers
Synthesis of 3,3-Disubstituted 2-Oxindoles by Deacylative Alkylation of 3-Acetyl-2-oxindoles
Ortega-Martínez, Aitor,Molina, Cynthia,Moreno-Cabrerizo, Cristina,Sansano, José M.,Nájera, Carmen
, p. 5203 - 5210 (2017/10/06)
An innovative and efficient monoalkylation and nonsymmetrical 3,3-dialkylation of oxindoles has been achieved. First, the monoalkylation of 3-acetyl-2-oxindoles can be performed in good yields under mild reaction conditions using alkyl halides and benzylt
2-Hydroxyindole Compounds. Alkylation of 3-Acetyl-1-benzyl-2-hydroxy-5-methoxyindole Under Basic Conditions
Huegel, Helmut M.,Greenwood, Richard J.,Mackay, Maureen F.
, p. 1953 - 1959 (2007/10/02)
Alkylation of 3-acetyl-1-benzyl-2-hydroxy-5-methoxyindole with benzyl bromide in the presence of base resulted in isolation of the C-alkylated product which has been shown by X-ray crystallographic analysis to be 3-acetyl-1,3-dibenzyl-5-methoxy-1,3-dihydr
