1469342-29-7Relevant academic research and scientific papers
A rational design strategy of the novel topoisomerase II inhibitors for the synthesis of the 4-O-(2-pyrazinecarboxylic)-4′-demethylepipodophyllotoxin with antitumor activity by diminishing the relaxation reaction of topoisomerase II-DNA decatenation
Zhao, Wei,Chen, Lu,Li, Hong-Mei,Wang, Duan-Ji,Li, Dong-Sheng,Chen, Tao,Yuan, Zhan-Peng,Tang, Ya-Jie
, p. 2998 - 3007 (2014)
A rational design strategy of the novel podophyllum topoisomerase II (Topo II) inhibitors for the synthesis of the esterification and amidation substituted 4′-demethylepipodophyllotoxin (DMEP) derivates was developed in order to discover the potential ant
