146936-48-3

Upstream product

• 354-38-1 2,2,2-trifluoroacetamide 
• 146936-46-1 [(2‐methanesulfinylethoxy)methyl]benzene 
• 146936-47-2 C₁₀H₁₅NO₂S 
• 407-25-0 trifluoroacetic anhydride 
• 146936-45-0 {[2‐(methylsulfanyl)ethoxy]methyl}benzene 
• 1462-37-9 bromoethyl-2-benzyl ether 

Relevant academic research and scientific papers

A kind of IDO inhibitor and use thereof

The embodiment of the invention provides general formula (I) compound or its pharmaceutically acceptable salts, stereoisomers, a tautomeric form each other, polymorphs, solvate, prodrug, metabolite or isotope derivatives, wherein the substituents R1

9-(SULFOXIMINOALKYL)GUANINE NUCLEOSIDES AS POTENTIAL ANTIHERPETIC AGENTS

A novel series of guanine nucleoside analogues 5-8 which contain a C-terminal sulfoximine have been synthesized.Key features of the synthesis include 1) the successful application of the trifluoroacetyl functional group as a stable, base-labile protecting group for the sulfoximine nitrogen and 2) the Mitsunobu-type coupling of alcohols 14 and 18-20 with purine 15.