146949-03-3

Upstream product

• 5133-68-6 ethyl N-carbethoxyvalerimidate 
• 96701-59-6 (2-chloro-5-nitrophenyl)hydrazine 
• 6283-25-6 H₂NC₆H₃(Cl)NO₂ 
• 146949-06-6 ethyl N-carbethoxy-valerimidate 

Downstream Products

• 147776-37-2 5-n-butyl-4-[[2'-[N-(2-chlorobenzoyl)sulfamoyl]biphenyl-4-yl]methyl]-2-(2-chloro-5-nitrophenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 146948-78-9 4-<<2'-biphenyl-4-yl>methyl>-5-n-butyl-2-<2-chloro-5-nitrophenyl>-2,4-dihydro-3H-1,2,4-triazol-3-one 

Relevant academic research and scientific papers

Potent and orally active angiotensin II receptor antagonists with equal affinity for human AT1 and AT2 subtypes

In order to block the effects induced by the interactions between angiotensin II (AII) and both AT1 and AT2 receptors, we have pursued the discovery of orally active non-peptide AII antagonists that exhibit potent and equal affinity

Triazolinone Biphenylsulfonamides as Angiotensin II Receptor Antagonists with High Affinity for Both the AT1 and AT2 Subtypes

Angiotensin II (AII), the endogenous peptide ligand of the AII receptor, has equivalent high affinity for both the AT1 and AT2 receptor subtypes while most of the reported nonpeptide AII antagonists are AT1-selective.In an

SUBSTITUTED 1,2,4-TRIAZOLES BEARING ACIDIC FUNCTIONAL GROUPS AS ANGIOTENSIN II ANTAGONISTS

Novel substituted triazolinone, triazolinethione, and triazolinimine compounds of the formula I are useful as angiotensin II antagonists. STR1