1469868-49-2Relevant academic research and scientific papers
Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 2: Discovery of novel [1,2,4]Triazolo[1,5-a]pyrimidines using a structure-guided core-refining approach
Wang, Liu,Tian, Ye,Chen, Wenmin,Liu, Hong,Zhan, Peng,Li, Dongyue,Liu, Huiqing,De Clercq, Erik,Pannecouque, Christophe,Liu, Xinyong
, p. 293 - 303 (2014/08/18)
Guided by crystal structures of HIV-1 RT/DAPY complex and molecular modeling studies, a series of novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives were rationally designed via structure-based core refining approach, synthesized through the readily acces
