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40775-75-5

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40775-75-5 Usage

Description

5-Hydroxy-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol is a chemical compound that serves as an important intermediate in the synthesis of various pharmaceutical agents. It possesses a unique triazolopyrimidine structure, which is known for its potential therapeutic properties.

Uses

Used in Pharmaceutical Industry:
5-Hydroxy-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol is used as a key intermediate in the synthesis of aralkyl amine-based triazolopyrimidine inhibitors. These inhibitors exhibit potent antimalarial activity and are being developed for the treatment of malaria.
Additionally, 7-Hydroxy-[1,2,4]triazolo[1,5-a]pyrimidin-5(1H)-one, a related compound, is also used in the synthesis of aralkyl amine-based triazolopyrimidine inhibitors for malaria treatment and antimalarial activity. This highlights the significance of the triazolopyrimidine framework in developing new therapeutic agents to combat malaria.

Check Digit Verification of cas no

The CAS Registry Mumber 40775-75-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,7,7 and 5 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 40775-75:
(7*4)+(6*0)+(5*7)+(4*7)+(3*5)+(2*7)+(1*5)=125
125 % 10 = 5
So 40775-75-5 is a valid CAS Registry Number.
InChI:InChI=1/C5H4N4O2/c10-3-1-4(11)9-5(8-3)6-2-7-9/h1-2,11H,(H,6,7,8,10)

40775-75-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-hydroxy-1H-[1,2,4]triazolo[1,5-a]pyrimidin-5-one

1.2 Other means of identification

Product number -
Other names 5,7-Dihydroxy-s-triazolo<2,3-a>pyrimidin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:40775-75-5 SDS

40775-75-5Relevant articles and documents

BCL6-targeting aromatic ring five-membered aromatic heterocyclic micromolecular organic compound and derivative and application thereof

-

Paragraph 0171-0174, (2021/03/24)

The invention discloses an aromatic ring five-membered aromatic heterocyclic micromolecular organic compound or related analogues or pharmaceutically acceptable salts thereof. The structures of the compound are shown as formulas (I-IX). The invention also

Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 2: Discovery of novel [1,2,4]Triazolo[1,5-a]pyrimidines using a structure-guided core-refining approach

Wang, Liu,Tian, Ye,Chen, Wenmin,Liu, Hong,Zhan, Peng,Li, Dongyue,Liu, Huiqing,De Clercq, Erik,Pannecouque, Christophe,Liu, Xinyong

, p. 293 - 303 (2014/08/18)

Guided by crystal structures of HIV-1 RT/DAPY complex and molecular modeling studies, a series of novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives were rationally designed via structure-based core refining approach, synthesized through the readily acces

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