1469894-57-2

Upstream product

• 111-16-0 heptanedioic acid 
• 75-65-0 tert-butyl alcohol 
• 10521-07-0 pimelic acid anhydride 

Downstream Products

• 1469894-64-1 1-(7-(benzyloxy)-2-(3,4-bis(benzyloxy)phenyl)-5-hydroxy-4-oxo-4H-chromen-3-yl)7-tert-butyl heptanedioate 
• 86013-78-7 tert-butyl 7-hydroxyheptanoate 

Relevant academic research and scientific papers

Molecular umbrella as a nanocarrier for antifungals

A molecular umbrella composed of two O‐sulfated cholic acid residues was applied for the construction of conjugates with cispentacin, containing a “trimethyl lock” (TML) or o‐dithiobenzylcarbamoyl moiety as a cleavable linker. Three out of five conjugates

CLIPTAC COMPOSITION

This invention relates to proteolysis targeting chimeric molecules formed from the intracellular self-assembly of precursors via bioorthogonal click chemistry (CLIPTACs), as well as related precursor compositions, methods and therapeutic applications.