1470058-05-9

Upstream product

• 152918-49-5 O-tert-butyl-4-amino-3-iodobenzylcarbamate 
• 98-59-9 p-toluenesulfonyl chloride 
• 103658-75-9 4-amino-3-iodo-N-benzylamine hydrochloride 
• 33348-34-4 4-amino-3-iodobenzonitrile 

Downstream Products

• 1470058-07-1 5-(O-tert-butoxycarbonyl)aminomethyl-2-(2-N,N'-bis-tert-butoxycarbonylguanidinoethyl)-1-N-(4-methylphenylsulfonyl)indole 
• 1470058-06-0 5-(O-tert-butoxycarbonyl)aminomethyl-2-(2-hydroxyethyl)-1-N-(4-methylphenylsulfonyl)indole 

Relevant academic research and scientific papers

In silico design, synthesis, and screening of novel deoxyhypusine synthase inhibitors targeting HIV-1 replication

The human enzyme deoxyhypusine synthase (DHS) is an important host cell factor that participates in the post-translational hypusine modification of eukaryotic initiation factor 5A (eIF-5A). Hypusine-modified eIF-5A plays a role in a number of diseases, in