14703-88-9

Basic information

• Product Name: 4-(N-METHYLAMINO)-3-NITRO PHENOL
• Synonyms: 4-(N-METHYLAMINO)-3-NITRO PHENOL;2-Nitro-4-hydroxy-N-methylaniline;Phenol, 4-(MethylaMino)-3-nitro-
• CAS NO: 14703-88-9
• Molecular Formula: C₇H₈N₂O₃
• Molecular Weight: 168.15
• Product Categories: API intermediates
• Mol File: 14703-88-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 349.2 °C at 760 mmHg
• Flash Point: 165 °C
• Appearance: /
• Density: 1.411 g/cm³
• Vapor Pressure: 2.38E-05mmHg at 25°C
• Refractive Index: 1.665
• CAS DataBase Reference: 4-(N-METHYLAMINO)-3-NITRO PHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(N-METHYLAMINO)-3-NITRO PHENOL(14703-88-9)
• EPA Substance Registry System: 4-(N-METHYLAMINO)-3-NITRO PHENOL(14703-88-9)

Safety Data

• Hazardous Substances Data: 14703-88-9(Hazardous Substances Data)

Usage

General Description

4-(N-Methylamino)-3-Nitrophenol is an aromatic compound with a complex molecular structure. It falls under the category of organic compounds, more specifically phenols. Phenols are compounds containing a phenol group -OH linked directly to an aromatic hydrocarbon group. The 4-(N-Methylamino)-3-Nitrophenol is composed of Nitrophenols, which are compounds containing a nitro group, and Aminophenols, which are organic compounds where the phenolic hydrogen is replaced by an amine group. 4-(N-METHYLAMINO)-3-NITRO PHENOL features a single methylamine group and a single nitro group on the phenol ring, which make it part of both aminophenols and nitrophenols. It is used primarily in the manufacture of dyes and as a chemical intermediate.

InChI:InChI=1/C7H8N2O3/c1-8-6-3-2-5(10)4-7(6)9(11)12/h2-4,8,10H,1H3

Upstream product

• 2105-96-6 4-fluoro-3-nitrophenol 
• 74-89-5 methylamine 
• 1414615-60-3 4-(4-methoxybenzyloxy)-2-nitrobenzenamine 
• 610-81-1 4-hydroxy-2-nitroaniline 

Downstream Products

• 611225-70-8 4-(4-Methylamino-3-nitro-phenoxy)-pyridine-2-carbonitrile 
• 850713-42-7 N-(4-(4-(methylamino)-3-nitrophenoxy)pyridin-2-yl)acetamide 
• 36242-36-1 2-nitro 4-hydroxy N-methyl N-carbethoxy acetyl aniline 
• 611226-50-7 3-amino-4-methylaminophenol 
• 1351414-28-2 4-(4-methylamino-3-nitrophenoxy)-pyridine-2-carboxylic acid [3-(2-oxo-pyrrolidin-yl)-propyl]-amide 

Relevant articles and documents

BENZIMIDAZOLE DERIVATIVES AND AZA-BENZIMIDAZOLE DERIVATIVES AS JANUS KINASE 2 INHIBITORS AND USES THEREOF

The present disclosure provides compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, and prodrugs thereof. The provided compounds may be kinase (e.g., Janus kinase (JAK), e.g., Janus kinase 2 (JAK2)) inhibitors. Also provided are pharmaceutical compositions and kits including the provided compounds. Further provided are methods of using the provided compounds, pharmaceutical compositions, and kits (e.g., for treating a disease (e.g., proliferative disease) in a subject in need thereof).