147030-70-4

Usage

Chemical structure

1-Propanone group attached to a 1,3-dioxolan-2-yl ring and a 4-methylphenyl group.

Common uses

Solvent in industrial and laboratory applications.

Solvency

High solvency for a wide range of substances.

Toxicity

Low toxicity.

Chemical versatility

Potential intermediate in the synthesis of other organic compounds.

Upstream product

• 18742-02-4 2-bromo-2-(2-ethyl)dioxolane 
• 874-60-2 4-methyl-benzoyl chloride 
• 764-48-7 ethyleneglycol vinyl ether 
• 619-41-0 4-(bromoacetyl)toluene 
• 99-94-5 p-Toluic acid 
• 37610-80-3 1,3-dioxolan-2-ylethylmagnesium bromide 

Downstream Products

• 147030-71-5 N-[2-(2-p-tolylpyrrol-1-yl)ethyl]acetamide 
• 122091-57-0 (-)-(R)-4-(p-tolyl)pentanal 
• 147580-43-6 3,4-Dihydro-1-methyl-6-p-tolylpyrrolo[1,2-a]pyrazine 
• 62506-81-4 4-oxo-4-(p-tolyl)butanal 

Relevant academic research and scientific papers

Dibromo-BODIPY as an Organic Photocatalyst for Radical-Ionic Sequences

A new dibrominated 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) is reported as a new metal-free photocatalyst. This BODIPY showed similar optoelectronic, electrochemical, and performance properties to those of Ru(bpy)3Cl2, one of the most common photocatalysts in a known radical-ionic transformation, such as the formation of 1,4-dicarbonyl compounds. Moreover, additional sequences in which the generated oxonium ion is trapped by an internal nucleophile were developed using this BODIPY photocatalyst. These new sequences allowed the straightforward preparation of ?3-alkoxylactones, monoprotected 1,4-ketoaldehydes, and dihydrofurans. This new catalyst, the methodology, and the forged functional groups could be important tools in organic synthesis.

Design and Synthesis of Novel and Potent Monoamine Oxidase Inhibitors

Reversible and selective monoamine oxidase-A inhibitors (RIMA's) like moclobemide (Aurorix) have rehabilitated the use of MAO inhibitors as drugs of choice in depression.Starting from the structure of moclobemide, we tried to identify novel

Catalytic Asymmetric Synthesis of γ-Hydroxy Ketones and Aromatic Hydroxy Ketones by the Chemo- and Enantio-selective Alkylation of keto Aldehydes with Dialkylzincs

Optically active γ-hydroxy ketones and aromatic hydroxy ketones with high (up to 96percent) enantiomeric excesses have been synthesized by the chemo- and enantio-selective addition of dialkylzincs to γ-keto aldehydes and aromatic keto aldehydes, respectively, using N,N-dibutylnorephedrine (DBNE) 1 and (1-methylpyrrolidin-2-yl)diphenylmethanol (DPMPM) 5 as chiral catalysts.The method provides a non-homoaldol approach to optically active γ-hydroxy ketones.

Pyrrolopyrazine derivatives

The novel pyrrolopyrazines of the general formula STR1 wherein one of R1 and R2 signifies aryl and the other signifies hydrogen, lower alkyl or aryl or R1 and R2 together with the two carbon atoms denoted by α and β signify the group A; STR2 R3 signifies hydrogen or lower alkyl and R4 signifies hydrogen or R3 and R4 together signify an additional C/N bond; R5 signifies hydrogen or lower alkyl; R6 signifies hydrogen or lower alkyl; R7 signifies hydrogen, halogen, lower alkyl, optionally substituted lower alkoxy, or C3-6 -cycloalkyl, C4-6 -cycloalkenyl, C3-6 -cycloalkyloxy, hydroxy, trifluoro- methanesulphonyloxy or optionally substituted benzyl- oxycarbonyloxy; and the dotted line signifies an optional additional C/C bond, and pharmaceutically acceptable acid addition salts of the compounds of formula I can be used in the control or prevention of illnesses or in the improvement of health, especially in the control or prevention of depressive states, cognitive disorders and neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease.