1470365-08-2Relevant academic research and scientific papers
Iron-catalyzed carbonylation-arylation of N-arylacrylamides for synthesis of oxindole derivatives
Jia, Fan,Liu, Kaisheng,Xi, Hui,Lu, Shenglin,Li, Zhiping
, p. 6337 - 6340 (2013)
An efficient method for oxindole synthesis is established by iron-catalyzed carbonylation-arylation of N-arylacrylamides with aldehydes. 3-Functionalized oxindoles are synthesized smoothly using FeCl3 as catalyst and TBHP as oxidant. The obtain
Silver-catalyzed decarboxylative acylarylation of acrylamides with α-oxocarboxylic acids in aqueous media
Wang, Hua,Guo, Li-Na,Duan, Xin-Hua
supporting information, p. 2222 - 2226 (2013/10/01)
A mild and efficient silver-catalyzed acyl- arylation of activated alkenes with easily available α-oxocarboxylic acids has been developed. The reactions provide a rapid access to a variety of functionalized oxindoles via a tandem decarboxylative radical cyclization strategy. This transformation proceeds well under mild reaction conditions and exhibits excellent functional group tolerance, affording the desired oxindoles in good to excellent yields.
