147107-70-8

Upstream product

• 92973-40-5 methyl (2R,3S)-3,4-O-isopropylidene-2,3,4-trihydroxybutanoate 
• 1379602-81-9 (2R)-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl](hydroxy)ethanoic acid sodium salt 
• 15042-01-0 5,6-O-isopropylidene-L-ascorbic acid 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 114185-07-8 ethyl (2R)-2-[(1S)-3,3-dimethyl(2,4-dioxolanyl)]-2-hydroxyacetate 
• 91274-05-4 (2S,3S)-1,2-O-isopropylidene-1,2,3,4-tetrol 
• 115114-86-8 3,4-O-isopropylidene-L-(S)-erythrulose 
• 183888-74-6 (S)-4-{(1S)-2-[(1,1-dimethylethyl)diphenylsilyloxy]-1-(hydroxy)ethyl}-2,2-dimethyl-1,3-dioxolane 

Downstream Products

• 147107-58-2 (R)-1-(tert-Butyl-diphenyl-silanyloxy)-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-propan-2-ol 
• 294626-17-8 (2S)-1-O-(tert-butyldiphenylsilyl)-2-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-4-pentene-1,2-diol 
• 188909-23-1 2-(tert-Butyl-diphenyl-silanyloxy)-1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethanone O-benzyl-oxime 
• 188909-26-4 2-(tert-Butyl-diphenyl-silanyloxy)-1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethanone O-benzyl-oxime 
• 863984-68-3 tert-butyl-[2-(2,2-dimethyl-[1,3]dioxolan-4-yl)-allyloxy]-diphenyl-silane 
• 294626-19-0 (2S,4'S)-2-(2,2-dimethyl-1,3-dioxolan-4-yl)-2-hydroxypent-4-enyl p-toluenesulfonate 
• 188909-47-9 (4R)-3-benzyloxy-4-methyl-4-((4R)-2,2-dimethyl-1,3-dioxolan-4-yl)-1,3-oxazolidin-2-one 
• 129141-48-6 (2R,3S)-3,4-O-isopropylidene-2-methyl-1,2,3,4-butanetetrol 
• 211044-92-7 (2R,3R)-3,4-O-isopropylidene-2-(N-benzyloxyamino)-2-n-butylbutane-1,3,4-triol 
• 211044-93-8 (2R,3R)-3,4-O-isopropylidene-2-(N-benzyloxyamino)-2-t-butylbutane-1,3,4-triol 
• 188909-37-7 O-Benzyl-N-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-phenyl-ethyl]-hydroxylamine 
• 188909-33-3 O-Benzyl-N-[(R)-1-(tert-butyl-diphenyl-silanyloxymethyl)-1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-pentyl]-hydroxylamine 
• 188909-36-6 O-Benzyl-N-[(R)-1-(tert-butyl-diphenyl-silanyloxymethyl)-1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-propyl]-hydroxylamine 
• 188909-29-7 O-Benzyl-N-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-methyl-ethyl]-hydroxylamine 

Relevant academic research and scientific papers

A rapid synthesis of hexofuranose-like iminosugars using ring-closing metathesis

(Chemical Equation Presented) Two new 1-N-iminosugars have been prepared as hexofuranose analogues in an efficient manner by an RCM-based route. Both 3,4-disubstituted pyrrolidines display moderate inhibitory activity against Mycobacterium smegmatis galac

Synthetic study of cnicin: Synthesis of the side chain and its esterification

Cnicin is a germacranolide sesquiterpene lactone that possesses potent inhibitory activity against the protozoan parasite Trypanosoma brucei, which causes human African trypanosomiasis (HAT). Although cnicin has an interesting structure and attractive biological activity, synthetic studies of cnicin have not yet been reported. This report describes the synthesis of the protected side chain carboxylic acid moiety at C8 of cnicin via two routes starting from L-ascorbic acid. In addition, esterification between the synthetic side chain and salonitenolide derivative, which can be achieved via hydrolysis of cnicin and protection of the primary alcohol, was conducted. Thus, a semi-synthesis of cnicin was achieved.

An efficient preparation of silylated derivatives of L-erythrulose 3,4- O-acetals

An efficient and reproducible procedure for the preparation of 1-O- silylated derivatives of several 3,4-O-acetals of erythrulose from the parent sugar is described.

Synthesis of protected enantiopure erythrulose derivatives

D- and L-Erythrulose derivatives 2-6 bearing protective O-silyl and O-benzyl groups in various positions were synthesized in enantiopure form from L-ascorbic acid, D-isoascorbic acid, and D-glucose. VCH Verlagsgesellschaft mbH, 1996.