147124-36-5Relevant academic research and scientific papers
SPIROINDOLINONES AS DDR1 INHIBITORS
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Page/Page column 65, (2017/09/07)
The present invention relates to compounds of formula (I): or pharmaceutically acceptable salts thereof, as well as processes for their manufacture, pharmaceutical compositions comprising them, and their use as medicaments.
A general oxindole synthesis
Quallich,Morrissey
, p. 51 - 53 (2007/10/02)
A general synthesis of indol-2(3H)-ones (oxindoles), was developed based on the addition of dimethyl malonate to commercially available halonitrobenzenes. The advantage of this route over many other oxindole syntheses was the regiochemical control of the substitution pattern on the aromatic ring.
