147162-29-6

Upstream product

• 504-29-0 2-aminopyridine 
• 100-00-5 4-chlorobenzonitrile 
• 115102-32-4 N-(4-chloro-phenyl)-N'-[2]pyridyl-hydrazine 
• 79917-37-6 2-nitrosopyridine 
• 106-47-8 4-chloro-aniline 
• 42860-85-5 1,1-dimethyl-N-(pyridin-2-yl)-λ⁴-sulfanimine 
• 932-98-9 1-chloro-4-nitroso-benzene 
• 54773-18-1 (E)-2-(phenyldiazenyl)pyridine 

Downstream Products

• 99852-67-2 N-(2,4-dichloro-phenyl)-N'-[2]pyridyl-hydrazine 
• 99866-64-5 2-(2,4-dichloro-phenyl-trans-azo)-pyridine 
• 129862-47-1 (ClC₆H₄NNC₅H₄N)HgCl₂ 
• 74896-03-0 N¹-(2-pyridyl)-4-chloro-o-phenylenediamine 

Relevant academic research and scientific papers

Improved synthesis of pyridyl-biaryl ring systems via benzidine rearrangements

The acid-catalyzed benzidine rearrangement of diazo compounds is known to involve several rearrangements with the major pathway being a [5,5] sigmatropic rearrangement to provide 4,4′-diaminobiaryls. A limitation of this rearrangement has been poor conversions with pyridyl systems. Herein, we address this long standing issue to furnish hetero-biaryls via a pyridinium salt in the presence of trimethylsilyl iodide.

Conversion of a Primary Amino Group into a Nitroso Group. Synthesis of Nitroso-Substituted Heterocycles

2-Aminopyridine, 2-amino-4-methylpyridine, 1-aminoisoquinoline, 2-aminopyrimidine, and 2-aminopyrazine have been converted to the corresponding nitroso compounds by reaction with dimethyl sulfide and N-chlorosuccinimide, deprotonation of the resulting sul