147165-82-0Relevant academic research and scientific papers
Exploring nitrone chemistry: Towards the enantiodivergent synthesis of 6-substituted 4-hydroxypipecolic acid derivatives
Merino, Pedro,Mannucci, Vanni,Tejero, Tomas
experimental part, p. 3943 - 3959 (2009/04/08)
A methodology for the stereoselective preparation of all-cis 6-substituted 4-hydroxypipecolic acid derivatives using nitrone chemistry, involving both nucleophilic additions and cycloadditions, is presented. The N-benzyl nitrone derived from 1,2-di-O-isop
High stereocontrol in the allylation of chiral non-racemic α-alkoxy and α-amino nitrones
Merino, Pedro,Delso, Ignacio,Mannucci, Vanni,Tejero, Tomas
, p. 3311 - 3314 (2007/10/03)
The stereocontrolled addition of allylic metals to chiral non-racemic nitrones promoted by the addition of Lewis acids is described. Whereas for α-alkoxy nitrones the stereocontrol depends on the Lewis acid used as an activator, for α-amino nitrones the d
Iodocyclization of Homoallylic Hydroxylamines Derived from D-Glyceraldehyde
Dhavale, Dilip D.,Gentilucci, Luca,Piazza, Maria Giulia,Trombini, Claudio
, p. 1289 - 1296 (2007/10/02)
The reaction of allylmagnesium chloride with nitrone 1 derived from D-glyceraldehyde affords two diastereoisomeric homoallylic hydroxylamines 2a and 3a which, after separation and O-silylation, are subjected to iodocyclization using N-iodosuccinimide.The
