147167-21-3Relevant academic research and scientific papers
Copper-Catalyzed Enantioselective Synthesis of β-Boron β-Amino Esters
López, Aurora,Clark, Timothy B.,Parra, Alejandro,Tortosa, Mariola
, p. 6272 - 6275 (2017)
In this report, the enantioselective, copper-catalyzed borylation of β-amidoacrylates is disclosed. A broad variety of biologically important α-aminoboronates has been prepared with consistently high levels of enantiocontrol using an inexpensive copper catalyst and a commercially available chiral ligand. The method can be applied to the synthesis of novel boron-containing dipeptides and hemiboronates.
Transition-metal-free synthesis of β-trifluoromethylated enamines with trifluoromethanesulfinate
Jiang, Huanfeng,Huang, Wei,Yu, Yue,Yi, Songjian,Li, Jiawei,Wu, Wanqing
supporting information, p. 7473 - 7476 (2017/07/12)
We have developed a transition-metal free trifluoromethylation protocol between enamines and CF3SO2Na. A wide range of β-trifluoromethyl substituted enamines were delivered in moderate to high yields with only E-configurations.
A facile one-pot domino reaction for the stereoselective synthesis of acryl derivatives promoted by Ca(OTf)2
Yaragorla, Srinivasarao,Saini, Pyare Lal,Pareek, Abhishek,Almansour, Abdulrahman I.,Arumugam, Natarajan
supporting information, p. 2034 - 2038 (2016/04/26)
A facile one-pot domino reaction for the stereoselective synthesis of acryl derivatives has been reported using alkaline earth catalyst [Ca(OTf)2]. Initially aryl amine reacts with ethyl propiolate to form β-enamino ester which further reacts w
Selective fluorescent sensor for mercury ions in aqueous media using a 1,4-dihydropyridine derivative
Homraruen, Daranee,Sirijindalert, Thirawat,Dubas, Luxsana,Sukwattanasinitt, Mongkol,Ajavakom, Anawat
, p. 1617 - 1621 (2013/02/25)
Novel 1,4-dihydropyridine (DHP) derivatives containing 3 carboxylic acid units are synthesized via cyclotrimerization of N-substituted β-aminoacrylates followed by basic hydrolysis of the triester. These DHP derivatives are readily soluble in aqueous media buffered at pH 8.0 and the solutions give blue fluorescent signals with quantum yields of 7-23%. One of these compounds, bearing a p-methoxyphenyl N-substituted group, shows specific fluorescent quenching with the mercuric ion (Hg2+). The fluorescent signal of the DHP derivative decays over a period of minutes to hours depending on the Hg2+ concentration, which implies that the sensing mechanism involves chemical reaction between the Hg2+ ion and the DHP compound. The 1H NMR and MS data suggest that Hg2+ mediates the oxidation of the DHP ring into a pyridinium ring. The event is useful for fluorescent detection of Hg2+ at the micromolar level within 30 min, with a detection limit of 0.2 μM in aqueous medium.
