1471806-85-5Relevant academic research and scientific papers
Copper-catalysed oxidative Csp3-H methylenation to terminal olefins using DMF
Liu, Jianming,Yi, Hong,Zhang, Xin,Liu, Chao,Liu, Ren,Zhang, Guoting,Lei, Aiwen
supporting information, p. 7636 - 7638 (2014/07/08)
A copper-catalysed direct oxidative Csp3-H methylenation to terminal olefins using DMF as one carbon source was developed. In this reaction, various functional groups were well tolerated, thus providing a simple way to construct arylvinylketones and arylvinylpyridines. The preliminary mechanistic investigations revealed that CH2 was from DMF (N-CH3).
Copper-catalyzed α-methylenation of benzylpyridines using dimethylacetamide as one-carbon source
Itoh, Masaki,Hirano, Koji,Satoh, Tetsuya,Miura, Masahiro
supporting information, p. 2050 - 2053 (2014/05/06)
The direct α-methylenation of benzylpyridines was achieved using N,N-dimethylacetamide (DMA) as a one-carbon source under copper catalysis. An intermediary species was detected at an early stage, and a possible mechanism was proposed. Additionally, α-oxygenation and dimerization of benzylpyridines could also be performed efficiently.
