147246-83-1

Basic information

• Product Name: tert-Butyl 3-(4-methylphenyl)-3-phenyl-propionate
• CAS NO: 147246-83-1
• Molecular Weight: 296.409
• Mol File: 147246-83-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-Butyl 3-(4-methylphenyl)-3-phenyl-propionate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl 3-(4-methylphenyl)-3-phenyl-propionate(147246-83-1)
• EPA Substance Registry System: tert-Butyl 3-(4-methylphenyl)-3-phenyl-propionate(147246-83-1)

Safety Data

• Hazardous Substances Data: 147246-83-1(Hazardous Substances Data)

Upstream product

• 27784-76-5 tert-butyl diethylphosphonoacetate 
• 100-52-7 benzaldehyde 
• 14990-09-1 tert-butyl cinnamate 
• 5720-05-8 4-methylphenylboronic acid 

Relevant articles and documents

Rh-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to 3-Arylpropenoates: Enantioselective Synthesis of (R)-Tolterodine

A highly enantioselective conjugate addition of arylboronic acids to 3-arylpropenoates is presented. The rhodium complexes obtained from deoxycholic acid derived binaphthyl phosphites showed good activity as well as very high enantioselectivity (ee up to 99 %) in the conjugate addition to different ethyl-3-arylpropenoates, allowing to obtain useful chiral building blocks for the synthesis of active pharmaceutical ingredients. The method was applied to the enantioselective synthesis of the antimuscarinic drug (R)-tolterodine.