14725-82-7

Upstream product

• 50695-53-9 N-(p-chlorobenzenesulfonyl)hydroxylamine 
• 292638-85-8 acrylic acid methyl ester 
• 100-03-8 4-chlorobenzenesulfinic acid 
• 106-54-7 p-Chlorothiophenol 
• 54696-23-0 Methyl 3-<(4-chlorophenyl)sulfenyl>propanoate 
• 14752-66-0 sodium p-chlorobenzenesulphinate 

Downstream Products

• 352672-21-0 C₁₆H₁₃ClN₂O₃S 
• 499190-56-6 3-[(4-chlorophenyl)sulfonyl]propanehydrazide 

Relevant academic research and scientific papers

Synthesis of alkyl aryl sulfones via reaction of N-arylsulfonyl hydroxyamines with electron-deficient alkenes

Alkyl aryl sulfones were prepared in high yields via the reaction of N-arylsulfonyl hydroxylamines with electron-deficient alkenes. These reactions have the advantages of simplicity, easily available starting materials and mild reaction conditions.

Method for preparing substituted ethyl aryl sulfone

The invention discloses a method for preparing substituted ethyl aryl sulfone. The method comprises the following steps: a compound shown in a formula II, a compound shown in a formula III and alkali are uniformly mixed in a solvent and are subjected to a coupling reaction, a compound shown in a formula I containing R2' as -CH2CH2R is obtained after the reaction is complete; or the method comprises the following steps: the compound shown in the formula II, ethyl propiolate and alkali are uniformly mixed in the solvent and then are subjected to the coupling reaction, and the compound shown in a formula I containing R2' as -CH=CH2=OOCH2CH3 is obtained after the reaction is complete. The method has the advantages of universality, convenience, simple reaction system, and mild reaction condition; the reaction can be amplified to a gram level, the reaction raw materials are simple and easily available, the used alkali and raw materials have the advantages of low cost and easy acquisition, the atom utilization rate is high, and solvent toxicity is low.

Synthesis and biological evaluation of some new 2,5-disubstituted 1,3,4-oxadiazoles from 3-(arylsulfonyl) propanehydrazides

Methyl acrylate on treatment with aryl thiols gives methyl 3-(arylthio) propanoates. The latter on oxidation with hydrogen peroxide followed by reaction with hydrazine hydrate gives 3-(arylsulfonyl) propanehydrazides. Two new series of 2,5-disubstituted-1

Addition of sulfinic acids to methacrylic derivatives

The kinetics of the addition of arenesulfinic acids to methacrylic derivatives were studied. The reactions were found to be second order over a range of concentrations from 0.01 to 0.10 M. For pH values ranging from 4 to 8, the following rate constants were obtained pH the methylacrylate, chloromethylacrylate, and bromomethylacrylate with benzenesulfinic acids (278 K) were investigated: 2.37 (± 0.2).10-4 M-1s -1, 2.60 (± 0.1).10-4 M-1s-1, 3.15 (± 0.3).10-4 M-1s-1. Copyright Taylor & Francis Group, LLC.