50695-53-9Relevant academic research and scientific papers
Carbethoxylating Agents as Inhibitors of Aldehyde Dehydrogenase
Nagasawa, Herbert T.,DeMaster, Eugene G.,Goon, David J. W.,Kawle, Sagar P.,Shirota, Frances N.
, p. 1872 - 1876 (1995)
N,O-Dicarbethoxy-4-chlorobenzenesulfohydroxamate (1c) and O-carbethoxy-N-hydroxysaccharin (6), both potential carbethoxylating agents, inhibited yeast aldehyde dehydrogenase (AlDH) with IC50's of 24 and 56 μM, respectively.The esterase activity of the enz
N-Hydroxy sulfonamides as new sulfenylating agents for the functionalization of aromatic compounds
Wang, Fu-Xiang,Zhou, Shao-Da,Wang, Chengming,Tian, Shi-Kai
supporting information, p. 5284 - 5288 (2017/07/10)
An unprecedented use of N-hydroxy sulfonamides as sulfenylating agents has been established. In the presence of catalytic amounts of iodine and N-hydroxysuccinimide, N-hydroxy sulfonamides participated in sulfenylation with indoles, 7-azaindole, N-methyl pyrrole, and 2-naphthol to afford structurally diverse thioethers in moderate to excellent yields with very high regioselectivity.
