147299-48-7

Upstream product

• 100-27-6 2-(4-nitrophenyl)ethanol 
• 51549-35-0 3',5'-bis-O-(tert-butyldimethylsilyl)-2'-deoxyguanosine 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 961-07-9 2'-Deoxyguanosine 
• 51549-35-0 3',5'-bis-O-(tert-butyldimethylsilyl)-2'-deoxyguanosine 

Downstream Products

• 148623-66-9 9-[(2R,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-6-[2-(4-nitro-phenyl)-ethoxy]-3,9-dihydro-purin-2-one 
• 148645-87-8 Trifluoro-methanesulfonic acid 9-[(2R,4S,5R)-4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-6-[2-(4-nitro-phenyl)-ethoxy]-9H-purin-2-yl ester 

Relevant academic research and scientific papers

Synthesis and hybridization properties of oligonucleotides containing polyamines at the C-2 position of purines: A pre-synthetic approach for the incorporation of spermine into oligodeoxynucleotides containing 2-(4,9,13-Triazatridecyl)-2′-deoxyguanosine

We have developed a synthesis of spermine-containing oligonucleotides (ODN-sper) which allows incorporation of multiple polyamine residues. This approach was based on the pertrifluoroacetylated 5′DMT-dGsper phosphoramidite synthon. Its coupling yield with

DNA interstrand cross-linking reactions of pyrrole-derived, bifunctional electrophiles: Evidence for a common target site in DNA

The site of DNA interstrand cross-linking identified by a family of pyrrole-derived bifunctional electrophiles was studied in vitro in synthetic DNA duplexes. This family includes reductively activated mitomycin C (1), oxidatively activated pyrrolizidine