147299-49-8

Upstream product

• 147299-45-4 2,3-dihydro-5-(3',4'-dichlorophenyl)-1H-pyrrolizine-6,7-dinitrile 
• 147299-48-7 3'-O,5'-O-bis(tert-butyldimethylsilyl)-O⁶-(2''-(4'''-nitrophenyl)ethyl)-2'-deoxyguanosine 
• 51549-35-0 3',5'-bis-O-(tert-butyldimethylsilyl)-2'-deoxyguanosine 
• 100-27-6 2-(4-nitrophenyl)ethanol 
• 132183-39-2 2-fluoro-O⁶-(2-(p-nitrophenyl)ethyl)-2'-deoxyinosine 
• 147299-46-5 6,7-bis(aminomethyl)-2,3-dihydro-5-(3',4'-dichlorophenyl)-1H-pyrrolizine 
• 961-07-9 2'-Deoxyguanosine 

Relevant academic research and scientific papers

DNA interstrand cross-linking reactions of pyrrole-derived, bifunctional electrophiles: Evidence for a common target site in DNA

The site of DNA interstrand cross-linking identified by a family of pyrrole-derived bifunctional electrophiles was studied in vitro in synthetic DNA duplexes. This family includes reductively activated mitomycin C (1), oxidatively activated pyrrolizidine