14731-14-7

Usage

Uses

Used in Pharmaceutical Synthesis:
5-(Bromoacetyl)-3-phenylisoxazole is used as a synthetic intermediate for the development of pharmaceuticals, leveraging its reactivity to modify the properties of target molecules and improve their therapeutic efficacy.
Used in Agrochemical Production:
In the agrochemical industry, 5-(Bromoacetyl)-3-phenylisoxazole is utilized as a key component in the synthesis of various agrochemicals, contributing to the enhancement of their performance and effectiveness in agricultural applications.
Used in Organic Compound Production:
5-(Bromoacetyl)-3-phenylisoxazole is employed as an intermediate in the production of a range of organic compounds, where its unique structure and reactivity are harnessed to facilitate the synthesis of complex molecules.
Used in Medicinal Chemistry Research:
5-(Bromoacetyl)-3-phenylisoxazole is used as a building block in medicinal chemistry, where its biological activities and structural features are explored for the discovery and development of new therapeutic agents.

InChI:InChI=1/C11H8BrNO2/c12-7-10(14)11-6-9(13-15-11)8-4-2-1-3-5-8/h1-6H,7H2

Upstream product

• 2048-69-3 5-acetyl-3-phenylisoxazole 
• 14776-02-4 1-(3-phenyl-isoxazol-5-yl)-ethanol 
• 698-16-8 benzohydroximoyl chloride 
• 54606-00-7 5-acetyl-4,5-dihydro-3-phenylisoxazole 

Downstream Products

• 115697-57-9 2-tert-Butylamino-1-(3-phenyl-isoxazol-5-yl)-ethanol 
• 521266-73-9 (2S)-1-({2-[4-(3-Phenyl-isoxazol-5-yl)-thiazol-2-ylamino]-ethylamino}-acetyl)-pyrrolidine-2-carbonitrile 
• 2048-69-3 5-acetyl-3-phenylisoxazole 
• 1266676-89-4 (4-methoxypyridin-2-yl)-[4-(3-phenylisoxazol-5-yl)-thiazol-2-yl]-amine 
• 1266676-75-8 (5-methylpyridin-2-yl)-[4-(3-phenylisoxazol-5-yl)-thiazol-2-yl]-amine 
• 1266676-91-8 (4-methylpyridin-2-yl)-[4-(3-phenylisoxazol-5-yl)-thiazol-2-yl]-amine 
• 1266676-92-9 (6-methylpyridin-2-yl)-[4-(3-phenylisoxazol-5-yl)-thiazol-2-yl]-amine 
• 1266676-83-8 isoquinolin-3-yl-[4-(3-phenylisoxazol-5-yl)-thiazol-2-yl]-amine 
• 1266676-88-3 (5-methoxypyridin-2-yl)-[4-(3-phenylisoxazol-5-yl)-thiazol-2-yl]-amine 
• 1006872-77-0 N-(3,3-diethoxypropyl)-4-(3-phenylisoxazol-5-yl)thiazol-2-amine 
• 131974-16-8 N-[4-(3-Phenyl-isoxazol-5-yl)-thiazol-2-yl]-oxalamic acid tert-butyl ester 
• 115697-58-0 2-Isopropylamino-1-(3-phenyl-isoxazol-5-yl)-ethanol 
• 49637-07-2 2-Bromo-1-(3-phenyl-isoxazol-5-yl)-ethanol 
• 104776-83-2 4-(3-Phenyl-isoxazol-5-yl)-thiazol-2-ylamine 

Relevant academic research and scientific papers

Synthesis and pharmacological characterization of new analogs of broxaterol

A series of isoxazole derivatives structurally related to broxaterol 1 has been prepared and tested for their potency to β1 and β2 adrenergic receptors. At variance with broxaterol, none of the tested compounds displayed agonistic activity. The 3-isopropenyl derivative 5f is the most potent antagonist both in the trachea and atria preparations.

In search of new chemical entities with spermicidal and anti-HIV activities

Several compounds belonging to 2-isoxazolines (4,5a-c), isoxazoles (3,6a-c) and 1-amino-1-cycloalkyl-2-substituted phenyl ethanes (16-18,a-e) have been synthesised and found to possess spermicidal activity. Out of these a couple of compounds (5a and 6a) exhibit anti-HIV activity. (C) Elsevier Science Ltd.

N-(4-isoxazolylthiazol-2-yl)oxamic acid derivatives as potent orally active antianaphylactic agents

A series of N-(4-isoxazolylthiazol-2-yl)oxamic acid derivatives was synthesized and tested on the passive cutaneous anaphylaxis (PCA) model in rats to verify its potential antianaphylactic activity. These compounds were prepared by reaction of an appropri

Synthesis of New Isoxazole Aminoalcohols

The preparation of new 1-isoxazolyl-2-amino-1-ethanol derivatives is described starting from the corresponding 1-isoxazolylethanones.It is also reported the synthesis of 1-(5-isoxazolyloxy)-3-amino-2-propanol compounds starting from the corresponding 5-ha