49637-07-2Relevant academic research and scientific papers
Synthesis and pharmacological characterization of new analogs of broxaterol
De Amici,Conti,Dallanoce,Kassi,Castellano,Stefancich,De Micheli
, p. 69 - 80 (2007/10/03)
A series of isoxazole derivatives structurally related to broxaterol 1 has been prepared and tested for their potency to β1 and β2 adrenergic receptors. At variance with broxaterol, none of the tested compounds displayed agonistic activity. The 3-isopropenyl derivative 5f is the most potent antagonist both in the trachea and atria preparations.
Synthesis of New Isoxazole Aminoalcohols
Chiarino, D.,Fantucci, M.,Sala, A.,Veneziani, C.
, p. 337 - 342 (2007/10/02)
The preparation of new 1-isoxazolyl-2-amino-1-ethanol derivatives is described starting from the corresponding 1-isoxazolylethanones.It is also reported the synthesis of 1-(5-isoxazolyloxy)-3-amino-2-propanol compounds starting from the corresponding 5-ha
