14731-27-2 Usage
Uses
Used in Pharmaceutical Industry:
5-Benzylamino-[1,3,4]thiadiazole-2-thiol is utilized as a key intermediate in the synthesis of various pharmaceuticals due to its versatile chemical reactivity and potential therapeutic effects. Its ability to modulate biological processes makes it a promising candidate for the development of new drugs.
Used in Cancer Treatment:
In oncology, 5-Benzylamino-[1,3,4]thiadiazole-2-thiol is studied for its potential as an anticancer agent, targeting the inhibition of tumor growth and the induction of apoptosis in cancer cells. Its unique structure allows it to interact with cellular targets, offering a new avenue for cancer therapy.
Used in Diabetes Management:
5-Benzylamino-[1,3,4]thiadiazole-2-thiol is also being investigated for its role in diabetes treatment, where it may help regulate glucose metabolism and improve insulin sensitivity, providing a novel approach to managing this chronic condition.
Used in Cardiovascular Disease Treatment:
5-BENZYLAMINO-[1,3,4]THIADIAZOLE-2-THIOL is being explored for its potential in treating cardiovascular disorders, possibly through its effects on lipid profiles and blood pressure regulation, offering a new strategy for cardiovascular health management.
Overall, 5-Benzylamino-[1,3,4]thiadiazole-2-thiol's multifaceted applications across different therapeutic areas highlight its importance in the ongoing quest for innovative pharmaceutical solutions.
Check Digit Verification of cas no
The CAS Registry Mumber 14731-27-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,7,3 and 1 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 14731-27:
(7*1)+(6*4)+(5*7)+(4*3)+(3*1)+(2*2)+(1*7)=92
92 % 10 = 2
So 14731-27-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H9N3S2/c13-9-12-11-8(14-9)10-6-7-4-2-1-3-5-7/h1-5H,6H2,(H,10,11)(H,12,13)
14731-27-2Relevant articles and documents
Synthesis and optimization of thiadiazole derivatives as a novel class of substrate competitive c-Jun N-terminal kinase inhibitors
De, Surya K.,Chen, Vida,Stebbins, John L.,Chen, Li-Hsing,Cellitti, Jason F.,Machleidt, Thomas,Barile, Elisa,Riel-Mehan, Megan,Dahl, Russell,Yang, Li,Emdadi, Aras,Murphy, Ria,Pellecchia, Maurizio
scheme or table, p. 590 - 596 (2010/05/02)
A series of thiadiazole derivatives has been designed as potential allosteric, substrate competitive inhibitors of the protein kinase JNK. We report on the synthesis, characterization and evaluation of a series of compounds that resulted in the identifica
Synthesis and antifungal activities of ω-(5-arylamino-1,3,4-thiadiazol-2-thio)-ω(1H-1,2,4-triazol-1-yl) acetophenones
Chu, Chang-Hu,Hui, Xin-Ping,Xu, Peng-Fei,Zhang, Zi-Yi,Li, Zhi-Chun,Liao, Ren-An
, p. 2436 - 2438 (2007/10/03)
Several ω-(5-arylamino-1,3,4-thiadiazol-2-thiol)-ω-(1H-1,2,4-triazol-1- yl)acetophenones 4a-i have been synthesized. The representative compounds exhibit some antifungal and plant growth regulatory activities. The structures of these compounds have been confirmed by elemental analyses, 1H NMR, IR and MS spectra.