1473354-91-4Relevant academic research and scientific papers
Studies on pyrrolidinones. On the synthesis of 5-aryl-2-pyrrolidones
Ghinet, Alina,Rigo, Benoit,Gautret, Philippe
, p. 1065 - 1072 (2013/09/23)
The optimization of the synthesis of 5-aryl-2-pyrrolidinones from decarbonylation of pyroglutamic acid in Eaton's reagent in the presence of aromatic derivatives is described. Four synthesized compounds were evaluated for their antiproliferative activity in the NCI-60 cancer cell lines panel.
