14736-62-0

Usage

InChI:InChI=1/C19H16O7/c1-21-11-7-14(22-2)17-15(8-11)26-19(20)16(18(17)23-3)10-4-5-12-13(6-10)25-9-24-12/h4-8H,9H2,1-3H3

Upstream product

• 186581-53-3 diazomethane 
• 14736-61-9 4-hydroxy-5,7-dimethoxy-3-(3,4-methylenedioxyphenyl)-1-benzopyran-2-one 
• 26664-86-8 (benzo[1,3]dioxol-5-yl)acetic acid ethyl ester 
• 77069-04-6 2-(benzo[1,3]dioxol-5-yl)malonic acid diethyl ester 
• 2555-38-6 4-hydroxy-5,7-dimethoxycoumarin 
• 90-24-4 2-hydroxy-4,6-dimethoxyacetophenone 
• 500-99-2 3,5-dimethoxyphenol 
• 852982-56-0 5,7-dimethoxy-3-diazo-benzopyran-2,4(3H)dione 
• 18107-18-1 diazomethyl-trimethyl-silane 

Relevant academic research and scientific papers

The rhodium carbenoid route to 3-aryl-4-hydroxycoumarins: Synthesis of derrusnin

3-Aryl-4-hydroxycoumarins have been obtained in satisfactory yields and selectivity through a Rh(II)-mediated arylation of diazocoumarin. The utility of this approach is demonstrated by synthesis of the natural product derrusnin.

New total synthesis of derrusnine

The thermal condensation of diethyl 3,4-methylenedioxyphenylmalonate lenedioxyphenyimalonate with 3,5- dimethoxyphenol (di-O-methylphloroglucinol) leads to the corresponding 3-(3,4-methylenedioxyphenyl)-4-hydroxy-5,7-dimethoxycoumarine which is methylated further into derrusnine.