14738-06-8 Usage
Uses
Used in Pharmaceutical Industry:
4-Chloro-N-(2,5-dichlorophenyl)benzenesulfonaMide, 97% is used as a pharmaceutical intermediate for the synthesis of various drugs. Its unique chemical structure and properties make it a valuable component in the development of new medications.
Used in Research Applications:
In addition to its use in the pharmaceutical industry, 4-Chloro-N-(2,5-dichlorophenyl)benzenesulfonaMide, 97% is also utilized in research settings. Its chemical properties and reactivity make it a useful compound for studying various chemical reactions and processes, contributing to the advancement of scientific knowledge in the field of chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 14738-06-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,7,3 and 8 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 14738-06:
(7*1)+(6*4)+(5*7)+(4*3)+(3*8)+(2*0)+(1*6)=108
108 % 10 = 8
So 14738-06-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H8Cl3NO2S/c13-8-1-4-10(5-2-8)19(17,18)16-12-7-9(14)3-6-11(12)15/h1-7,16H
14738-06-8Relevant academic research and scientific papers
Carbamate-appended N-alkylsulfonamides as inhibitors of γ-secretase
Bergstrom, Carl P.,Sloan, Charles P.,Lau, Wai-Yu,Smith, David W.,Zheng, Ming,Hansel, Steven B.,Polson, Craig T.,Corsa, Jason A.,Barten, Donna M.,Felsenstein, Kevin M.,Roberts, Susan B.
, p. 464 - 468 (2008/12/21)
The synthesis and γ-secretase inhibition data for a series of carbamate-appended N-alkylsulfonamides are described. Carbamate 54 was found to significantly reduce brain Aβ in transgenic mice. 54 was also found to possess markedly improved brain levels in transgenic mice compared to previously disclosed 1 and 2.
